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Elephantiasis is not a misnomer
The meaning is not "disease caused by elephants" but disease causing deformity that makes the, affected limb look like that of an elephant because of the soft tissue swelling and skin hardening. Thus the name refers to the morphological features of the condition and not to its cause.
REF
1. HISTORY OF ELEPHANTIASIS, HIRAK BEHARI ROUTH M.B., B.S.*, KAZAL REKHA BHOWMIK M.B., B.S.
Article first published online: 31 MAY 2007, DOI: 10.1111/j.1365-4362.1993.tb01418.x
2. elephantiasis (n.) 1580s, from Greek elephantos, genitive of elephas "elephant" (see elephant) + -iasis "pathological or morbid condition." It refers to two diseases, one characterized by thickening of a body part (E. Arabum), the other, older meaning is "disease characterized by skin resembling an elephant's" (E. Græcorum, also called Egyptian leprosy).2001-2012 Douglas Harper Etymology Dictionary